Discovery® Cyano HPLC Column

eCl@ss: 32110501

Features and Benefits

• Low hydrophobicity for rapid elution of hydrophobic analytes
• Excellent peak shape and retention of strongly basic analytes
• Retention of polar analytes
• Unique selectivity
• Significantly less retention than C18 (typically requires lower % organic mobile phase)
• Stable, low-bleed LC-MS separations
• Compatible with highly aqueous organic phases

Legal Information
SUPELCOSIL LC-ABZ phase has a unique deactivation technology which provides excellent reversed-phase performance for basic compounds, as well as those that are acidic, polar neutral, and non-polar. Silanol suppressing practices such as using competing amines, operating at high ionic strength, and adjusting mobile phases to pH extremes are typically not required to obtain good peak shape on the LC-ABZ phase.

Legal Information
Discovery is a registered trademark of Sigma-Aldrich Co. LLC

Feature: endcapped

Extent of Labeling: 4.5% Carbon loading

Limit: ≤70°C temp. range

Application(s): HPLC: suitable

L × I.D.: 25 cm × 4.6 mm

Surface Coverage: 3.5 μmol/m²

Impurities: <10 ppm metals

Matrix: silica gel, high purity, spherical base material

Matrix Active Group: cyano phase

Particle Size: 5 μm

Pore Size: 180 Å

Surface Area: 200 m²/g

Operating pH-range: 2 – 8

Suitability: suitable for L10 per USP

Mode of Chromatography: Hydrophilic interaction (HILIC); Normal phase; Reversed phase