NUCLEOSHELL® core-shell silica phases for HPLC
NUCLEOSHELL® Core-shell technology provides
- Better resolution at lower back pressure and shorter retention time
- Solid core of silicon dioxide
- Homogeneous shell of porous silica
- Highest efficiency compared to traditional totally porous materials
- Particle size 2.7 µm (core 1.7 µm); specific surface 130 m2/g
- RP 18 and RP 18plus phases are also available with particle size 5 µm (core 3.8 µm); specific surface 90 m2/g
- Lower back pressure also allows use on conventional LC systems
- Pressure stability up to 600 bar
NUCLEOSHELL® PFP
Pentafluorophenylpropyl modification with multi-endcapping, USP L43
Key features:
- Based on core-shell particle technology for fast and efficient HPLC
- Hydrophobic phase with alternative selectivity in comparison to classical C18 modifications
- Suitable for LC/MS
- Separation principle based on 4 retention mechanisms: polar interactions (H bonds), dipole-dipole interactions, π-π interactions, hydrophobic interactions
Technical characteristics:
- Pentafluorophenyl propyl modification, multi-endcapped
- Pore size 90 Å
- Particle size 2.7 μm
- pH stability 1–9
- Carbon content ~ 3 %
Recommended application: Aromatic and unsaturated compounds, phenols, halogenated hydrocarbons, isomers, polar compounds like pharmaceuticals, antibiotics; high retention of basic compounds
| Thomas No | Mfr No | Description |
|---|---|---|
| 1150F88 | 763532.20 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 50 mm, ID: 2mm, USP: L43, 1 Column |
| 1150F89 | 763532.30 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 50 mm, ID: 3mm, USP: L43, 1 Column |
| 1150F90 | 763532.40 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 50 mm, ID: 4mm, USP: L43, 1 Column |
| 1150F91 | 763532.46 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 50 mm, ID: 4.6mm, USP: L43, 1 Column |
| 1150F92 | 763534.20 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 100 mm, ID: 2mm, USP: L43, 1 Column |
| 1150F93 | 763534.30 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 100 mm, ID: 3mm, USP: L43, 1 Column |
| 1150F94 | 763534.40 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 100 mm, ID: 4mm, USP: L43, 1 Column |
| 1150F95 | 763534.46 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 100 mm, ID: 4.6mm, USP: L43, 1 Column |
| 1150F96 | 763536.20 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 150 mm, ID: 2mm, USP: L43, 1 Column |
| 1150F97 | 763536.30 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 150 mm, ID: 3mm, USP: L43, 1 Column |
| 1150F98 | 763536.40 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 150 mm, ID: 4mm, USP: L43, 1 Column |
| 1150F99 | 763536.46 | HPLC column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 150 mm, ID: 4.6mm, USP: L43, 1 Column |
| 1150G00 | 763538.20 | HPLC guard column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 4 mm, ID: 2mm, USP: L43, 3 guard columns |
| 1150G01 | 763538.30 | HPLC guard column (analytical), NUCLEOSHELL PFP, 2.7 µm, length: 4 mm, ID: 3mm, USP: L43, 3 guard columns |
