NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure
- Wide acceptance as routine packings for very different fields of chromatography
- One of the first spherical silicas used in HPLC
- Developed in the early seventies, it became a world-renowned HPLC packing
- Still found in many analytical and preparative application
- An absolutely reliable choice in HPLC
- The largest variety of modified HPLC silicas available on the market
NUCLEOSIL® C4
- Butyl modified silica phases for HPLC
- USP L26
- Medium density modification, endcapped
Features
- Endcapped phases for RP and ion-pairing chromatography
- Available pore sizes 120 and 300 Å
- Particle size 5 µm
- pH stability at 20 °C: 2–8
- Carbon content ~ 2 % C
Separation mechanism based on hydrophobic (van der Waals) interactions, some residual silanol interactions
Retention times are shorter than on C8 and C18 phases
| Thomas No | Mfr No | Description |
|---|---|---|
| 1152Y67 | 720096.46 | HPLC column (analytical), NUCLEOSIL 120-5 C4, length: 250 mm, ID: 4.6mm, USP: L26, 1 Column |
| 1152Y49 | 720059.40 | HPLC column (analytical), NUCLEOSIL 300-5 C4, length: 250 mm, ID: 4mm, USP: L26, 1 Column |
| 1152Y50 | 720059.46 | HPLC column (analytical), NUCLEOSIL 300-5 C4, length: 250 mm, ID: 4.6mm, USP: L26, 1 Column |
| 1152Z69 | 721083.30 | HPLC guard column (analytical), NUCLEOSIL 120-5 C4, length: 4 mm, ID: 3mm, USP: L26, 3 guard column |
