Raptor™ FluoroPhenyl LC Columns (USP L43)

Restek chemists became the first to combine the speed of superficially porous particles (also known as SPP or “core-shell” particles) with the resolution of highly selective USLC technology. This new breed of chromatographic column allows you to more easily achieve peak separation and faster analysis times without expensive UHPLC instrumentation.

Restek has now extended the speed and reliability of Raptor column technology into the HILIC realm with the addition of Raptor FluoroPhenyl columns. Restek’s Raptor FluoroPhenyl phase offers chromatographers the ability to run in reversed-phase or HILIC mode for a variety of compounds. The Restek Raptor FluoroPhenyl column is also amenable to LC-MS because it is extremely reliable and efficient with acidic mobile phases.

Stationary Phase Category: Pentafluorophenyl propyl (L43)
Ligand Type: Fluorophenyl
Particle: 2.7 µm or 5 µm superficially porous silica (SPP or “core-shell”)
Pore Size: 90 Å
Carbon Load: 4% (2.7 µm), 3% (5 µm)
End-Cap: no
Surface Area: 150 m²/g (2.7 µm) or 100 m²/g (5 µm)
Recommended Usage:
pH Range: 2.0–8.0
Maximum Temperature: 80°C
Maximum Pressure: 600 bar/8,700 psi (2.7 µm) or 400 bar/5,800 psi (5 µm)

Properties:

• Capable of both reversed-phase and HILIC separations.
• Ideal for increasing sensitivity and selectivity in LC-MS analyses.
• Offers increased retention for charged bases.
• Part of Restek’s Raptor LC column line featuring 1.8, 2.7, and 5 µm SPP core-shell silica.
• Switch to a Raptor FluoroPhenyl LC column when you need more retention and selectivity for basic and hydrophilic compounds than you can achieve on a C18.

Switch to a Raptor FluoroPhenyl LC column when:

• Limited retention and selectivity are observed on a C18 for basic compounds
• You need increased retention of hydrophilic compounds
• Free-Turn architecture lets you change cartridges by hand without breaking inlet/outlet fluid connections—no tools needed.
• Patented titanium hybrid ferrules can be installed repeatedly without compromising high-pressure seal.
• Auto-adjusting design provides ZDV (zero dead volume) connection to any 10-32 female port.

Maximum cartridge pressure: 1,034 bar/15,000 psi* (UHPLC), 600 bar/8,700 psi (2.7 µm); 400 bar/5,800 psi (5 µm)

* For maximum lifetime, recommended maximum pressure for UHPLC particles is 830 bar/12,000 psi.