NUCLEODUR® C18 Gravity-SB HPLC Columns

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

• Totally spherical particle shape
• Outstanding surface microstructure
• High pressure stability
• Low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL’s pioneering research in chromatography for almost 50 years.

NUCLEODUR® C18 Gravity-SB

Monomeric octadecyl modification with polar selectivity, USP L1

Key features:

• Hydrophobic C18 phase with distinct polar selectivity, ideal for method development, better retention of early eluting substances
• Excellent performance under highly aqueous conditions
• Suitable for LC/MS due to low bleeding characteristics

Technical characteristics:

• Monomeric octadecyl modification, extensive endcapping;
• Pore size 110 Å
• Available particle sizes 1.8 μm (UHPLC), 3 μm and 5 μm
• Carbon content 13 %;
• pH stability 1–9

Recommended application:

• Overall sophisticated analytical separations, especially for polar compounds, e.g., antibiotics, water-soluble vitamins, organic acids